Dr. Martin Harris (Liam Neeson) and his wife Liz (January Jones) arrive in Berlin for a biotechnology summit. Upon arriving at their hotel, Martin realizes he forgot his briefcase at the airport. He takes a taxicab driven by Gina (Diane Kruger), but on the way to the airport, the cab crashes off a bridge into the river after narrowly avoiding a refrigerator that falls off a delivery truck in front of them. Martin is knocked unconscious upon impact, but Gina saves him from drowning before fleeing from the scene. On Thanksgiving day, he comes to at the hospital after being in a coma for four days.Martin returns to his hotel, only to discover another man (Aidan Quinn) with his wife, who tells hotel security she does not know him. He attempts to contact his old colleague Prof. Rodney Cole (Frank Langella), who is unavailable due to Thanksgiving in the U.S. Martin then heads to the office of Prof. Bressler (Sebastian Koch), whom he is scheduled to meet that day. However, he sees the impostor (known as "Martin B") already in a meeting with Bressler. As Martin attempts to prove his identity, Martin B shows him his ID and family photo - both of which have Martin's name, only with his face replaced by that of the impostor. Disillusioned by the identity crisis, Martin falls unconscious and finds himself back at the hospital, where he undergoes an MRI to see if the accident had caused any head trauma. An assassin sent to target him kills Dr. Farge (Karl Markovics) and Nurse Gretchen Erfurt (Eva Löbau), but Martin manages to escape assassination.
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